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The run of form from the Gunners has left the club in fourth place in the standings, and just one point adrift of third-placed Chelsea.
Manager Unai Emery has also been boosted by his team’s 4-2 comeback victory over Tottenham Hotspur at the Emirates Stadium on Sunday afternoon.
The Spaniard has a number of selection dilemmas ahead of Wednesday’s match, and here Sports Mole looks at how his team could line up in the North-West
Emery will have to make do without Granit Xhaka at Old Trafford after the Switzerland international picked up a fifth yellow card of the season at the weekend.
Alexandre Lacazette has also returned to full fitness after a minor injury, and the Frenchman could potentially be handed a return to the starting lineup.
The defence and wing-backs are likely to remain the same, with Nacho Monreal still unavailable due to a thigh injury and Laurent Koscielny short of match fitness.