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Ozil has trained all week and may line up in the No.10 role, behind the front two of Alexandre Lacazette and Pierre-Emerick Aubameyang.
The midfield three behind the No.10 is expected to stay the same as it was against Chelsea, with Granit Xhaka, Lucas Torreria and Matteo Guendouzi set to start.
Emery has some big decisions to make at the back. Laurent Koscielny, so impressive against Chelsea, could be given the night off to protect his fitness levels ahead of Tuesday night’s game with Cardiff.
That would see Shkodran Mustafi slot back in alongside Sokratis in the heart of the back four.
Emery may decide to start with Nacho Monreal at left-back in favour of Sead Kolasinac, with Ainsley Maitland-Niles covering on the opposite side of the defence following the injury to Hector Bellerin.
Petr Cech, who will retire at the end of the season, will start in goal, with Bernd Leno on the bench.